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Original Article

ECB. 2016; 5(5): 185-188


AN EFFICIENT MICROWAVE-ASSISTED SYNTHESIS OF 2,3- DIHYDROQUINAZOLIN-4(1H)-ONES BY A THREE COMPONENT REACTION UNDER CATALYST- AND SOLVENT-FREE CONDITIONS

Arpita Das Gupta, Nayim Sepay, Asok K. Mallik.




Abstract

An efficient and green synthesis of 2,3-dihydroquinazolin-4(1H)-ones by microwave-assisted reaction of isatoic anhydride, ammonium
acetate and an aldehyde or a ketone under catalyst- and solvent-free conditions is described.

Key words: 2,3-Dihydroquinazolin-4(1H)-ones, microwave irradiation, catalyst- and solvent-free synthesis, isatoic anhydride, aldehydes, ketones.






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