Background: Noninvasive ventilation (NIV) is considered for the treatment of pediatric acute respiratory failure (ARF). Conventional NIV modes have a higher asynchrony index (AI) when compared to Noninvasive Neurally Adjusted Ventilatory Assist (NIV NAVA) mode. The present study aiming to compare the AI and clinical outcomes during NIV NAVA vs. conventional NIV in pediatrics aged between one month and 18 years . Methodology: This is a systematic review of clinical trials conducted between April and May 2020 in the electronic databases Cochrane Library, Embase, Lilacs, Pubmed/Medline, Scopus and Web of Science. Results: Four out of 184 studies were eligible for qualitative synthesis, presenting 50% high risk of bias in the randomization, allocation, and other bias. The sample analyzed 39 participants, aged between 35 days and 15 years with male predominance (61.5%). The primary outcome analyzed in three out of four studies was the significant decrease (p
Key words: Noninvasive Ventilation, Child, Support, Interactive Ventilatory, Neurally Adjusted Ventilatory Assist.
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