Objective: In this case report, we report for first the time the presence of porcine deltacoronavi¬rus (PDCoV) in Peru (October 2019) and Latin America, and we present a control and eradication program using feedback (exposure)/controlled homogenization in a pig farm.
Materials and Methods: This farm is located in the eastern jungle of Peru. Initially, clinical signs that appeared to be infectious diarrhea were detected, but the disease rapidly progressed to green diarrhea, vomiting, and increased mortality in piglets. These symptoms were compatible with those produced by porcine epidemic diarrhea virus and transmissible gastroenteritis virus, but also with PDCoV. Because the disease could not be diagnosed by clinical signs and symptoms, analysis by real-time polymerase chain reaction was used. Implementation of a feedback/con¬trolled homogenization program was quickly planned, accompanied by the closure of the farm, animal and farm health strategies, and its respective monitoring.
Results: At the farm level, between 1 and 9 weeks after application of the program, the samples were positive for PDCoV, but at week 10, they were negative. At week 12, the weaned and fatten¬ing piglets gradually became populated as negative animals. In the follow-up before the opening of the farm, all the piglets were negative. In the final verification, gilts (week 35) entered the breeding area as replacements only after being tested negative for PDCoV.
Conclusion: A rigorous feedback/controlled homogenization program and complementary mea¬sures led to eradicating PDCoV from the farm.
Coronavirus; diarrhea; feedback; piglets; RT-PCR; viral exposure
Contributing factors common to COVIDâ€‘19 and gastrointestinal cancer.
Kostoff RN, Briggs MB, Kanduc D, Shores DR, Kovatsi L, Drakoulis N, Porter AL, Tsatsakis A, Spandidos DA
Oncology reports. 2022; 47(1):
Systematic review and meta-analysis of the papillomavirus prevalence in breast cancer fresh tissues.
Gomes de Oliveira G, GonĂ§alves AK, EleutĂ©rio J, Pinheiro LGP
Breast disease. 2022; 41(1): 123-132
Geographic distribution and time trend of human exposure of Di(2-ethylhexyl) phthalate among different age groups based on global biomonitoring data.
Qu J, Xia W, Qian X, Wu Y, Li J, Wen S, Xu S
Chemosphere. 2022; 287(Pt 2): 132115
Current trends in gene therapy for retinal diseases (Review).
Moraru AD, Costin D, Iorga RE, Munteanu M, Moraru RL, Branisteanu DC
Experimental and therapeutic medicine. 2022; 23(1): 26
induces innate cytokine responses that potentially provide a protective benefit against COVID-19: A single-arm, double-blind, prospective trial combined with an cytokine response assay.
Kageyama Y, Nishizaki Y, Aida K, Yayama K, Ebisui T, Akiyama T, Nakamura T
Experimental and therapeutic medicine. 2022; 23(1): 20