Home|Journals|Articles by Year|Audio Abstracts

Original Article

ECB. 2016; 5(1): 14-17


Balbir Kumar, Goutam Brahmachari, Bubun Banerjee, Khondekar Nurjamal, Rajni Kant, Vivek K. Gupta.


The title compound, 2-amino-4-(3-bromophenyl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile (C18H17BrN2O2), was
synthesized, in 86% yield, by one-pot multicomponent reaction of 3-bromobenzaldehyde, malononitrile and dimedone using 10 mol % urea
as an organo-catalyst at room temperature. It crystallizes in the monoclinic space group C 2/c with the unit-cell parameters: a= 23.557(2),
b= 9.2963(7), c= 15.7502(12) Å, β = 93.430(8)o
and Z = 8. The crystal structure was solved by direct methods using single-crystal X-ray
diffraction data collected at room temperature and refined by full-matrix least-squares procedures to a final R-value of 0.0585 for 1411
observed reflections. The packing between the molecules within the unit cell is stabilized by N-H..O and N-H…N type of intermolecular
hydrogen interactions.

Key words: Crystal structure, direct methods, hydrogen interactions.

Full-text options

Share this Article

Online Article Submission
• ejmanager.com

ejPort - eJManager.com
Review(er)s Central
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under Creative Commons Attribution 4.0 International License (CC BY), which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.