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Original Article

ECB. 2015; 4(10): 460-462


A NEW REAGENT FOR THE SYNTHESIS OF PYRAZOLO[4,3-e][1,2,4]TRIAZOLO[1,5-c]PYRIMIDINES

Khidmet S. Shikhaliev, Evgeniya A. Kosheleva, Lyudmila F. Ponomaryeva, Michael Yu. Krysin.


Abstract

Tandem reaction of N'-(4-cyano-1-phenyl-1H-pyrazol-5-yl)-N,N-dimethylimidoformamide (6) with acylhydrazines in N,Ndimethylacetamide leads to the formation of 2-R-7-phenyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidines (10a-f).

Key words: pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidines; aminopyrazole; acylhydrazines; N,N-dimethylformamide dimethylacetal; tandem reaction.






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