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Original Research

ECB. 2022; 11(3): 8-13


ANTI BACTERIAL ACTIVITY OF NONSTEROIDAL ANTI INFLAMMATORY AGENTS AND THEIR DERIVATIVES

Sajjad A. Hafedh, Sahar A. Hussein, Noor H. Naser*.




Abstract

The review show the role of Nonsteroidalanti inflammatory agents and their moieties in key biological processes.
They are wide used group of medicines derivatives utilized to treat a variety of medical pain conditions. One of these classes
of drugs is naproxen that is commonly utilized. Despite its gastrointestinal side effects, most of this group of medicines was
safely utilized for decades due to their low cost. They have reverse activities to inflammation, also pharmacological activity
of non-steroidal anti-inflammatory medicines, such as antibacterial properties, have been the subject of considerable research
in recent years, NSAIDs medicines works in manner that inhibiting all enzymes of cyclooxygenase group. This mechanism
is interested in the possibility that cyclooxygenase two enzyme inhibits microbial development, which is characterized by the
appearance of cyclooxygenase two enzyme. NSAIDs having derivatives molecules, they were always explored.

Key words: Anti-bacterial activity, Nonsteroidal, inflammatory agents






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