Background: Treatment of locally advanced endometrial cancer in patients with transplanted pelvic kidney requires precautions because of its anatomical position next to target volumes.
Case Presentation: We report a case of 42-year-old woman with a right renal transplant for 3 years diagnosed with endometrial cancer for which she underwent total abdominal hysterectomy with bilateral salpingo-oophorectomy and pelvic lymphadenectomy. Adjuvant Radiotherapy (RT) was planned through intensity modulated RT (IMRT) with 45 Gy in 25 fractions followed by vaginal brachytherapy (5 Gy × 2 sessions) . Planning with IMRT quantified a mean dose of 2 Gy and maximum dose of 10 Gy over the transplanted kidney. This dose was further reduced with a comparative plan of three-dimensional conformal RT (3DCRT), recording a mean dose of 1 Gy and maximum dose of 5 Gy to the transplanted kidney. 3DCRT plan was accepted and delivered. At 2-year follow-up, patient is disease free with normal renal function.
Conclusion: In the presence of advanced techniques, 3DCRT is still a valid radiation technique to keep the critical organ dose under acceptable dose-volume constraints without compromising the target volume.
Renal transplant, endometrium carcinoma, 3DCRT, IMRT, case report
Neonatal Transplant in Hypoxic Injury.
Zheng T, Weiss MD
Methods in molecular biology (Clifton, N.J.). 2022; 2389(): 155-164
Lectin Affinity Chromatography for the Discovery of Novel Cancer Glycobiomarkers: A Case Study with PSA Glycoforms and Prostate Cancer.
Llop E, Peracaula R
Methods in molecular biology (Clifton, N.J.). 2022; 2370(): 301-313
Functional and immunological peculiarities of peripheral nerve allografts.
Roballo KCS, Gigley JP, Smith TA, Bittner GD, Bushman JS
Neural regeneration research. 2022; 17(4): 721-727
Metastatic atypical renal tumour with metanephric characteristics treated with Sunitinib.
Mohammad H, Madsen K, Graumann O, Loya AC, Jensen NV, Dahlrot RH
Urology case reports. 2022; 40(): 101880
Upper tract urothelial carcinoma presenting at a bifurcation of a partially duplicated left ureter: A minimally invasive approach.
Sarver J, Memo M
Urology case reports. 2022; 40(): 101879