In the present work, synthesis of silver nanoparticles has been done using a particular variety of medicinal plant extract. Silver
nanoparticles have unique optical, electrical, and thermal properties that play an indispensable role in drug delivery, diagnostics, imaging,
sensing, gene delivery, artificial implants and tissue engineering. . We used an environmentally friendly extracellular biosynthetic technique
for the production of the AgNPs. The reducing agents used to produce the nanoparticles were from aqueous extracts made from the leaves
of Ficus microcarpa. We have synthesized silver nano particles by adding the 80 ml of 1 mM silver nitrate solution into the plant extract
and characterized by UV-Vis absorption spectroscopy, Infra-red spectroscopy. The UV-Visible spectrum showed a peak at 451 nm
corresponding to the Plasmon absorbance of the AgNPs. Moreover, use of plant extracts also reduces the cost of microorganism isolation
and culture media enhancing the cost competitive feasibility over nanoparticle synthesis by microorganisms. The antibacterial efficacy also
determined by disc diffusion method with Bacillus cereus, Escherchia coli, Klebsiella pneumonia, Staphylococcus aureus and it showed
that high level of inhibition. Further, efficient antimicrobial activity of the synthesized silver nanoparticles proves the application potential
of green synthesis in the area of nano-medicine
Key words: Plant extracts, Ficus microcarpa, silver nanoparticle synthesis and antibacterial activity
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