Introduction: Selenium binding protein 1 (SBP1) is a cytosolic protein and a low serum level of SBP1 is a marker for women at risk of ovarian failure and infertility. The aim of this study is to meet the need for a marker that can be used in the clinic as an alternative to anti-Mullerian hormone (AMH) in primary infertile patients.
Materials and Methods: A total of 82 women, 63 in the study and 19 in the control groups, were included in the study. On the 2nd or 3rd day of the menstruation, patients were examined with transvaginal sonography (TVS) and the number of antral follicles (AFs) was calculated. Then, laboratory blood samples were taken to measure AMH, SBP1, FSH, LH, E2, prolactin and TSH values.
Results: SBP1 levels were similar in the study and control groups. No statistically significant relationship was found between SBP1 and AMH, AFs, BMI, age, pregnancy outcome, FSH, LH, and E2 parameters. Measures in which the success of distinguishing individuals from the study group and the control group was significant were found only as age and AMH variables.
Conclusions: AMH shows the number of primordial follicles, provides information about the health status of the ovarian tissue, and the serum level of AMH decreases with years, and there is a weak relation between SBP1 and these values, but there is a statistically insignificant relationship, information about ovarian tissue such as AMH; these also suggest that women can use it as an ovarian reserve test regardless of their cycle.
Key words: primary infertility, selenium binding protein 1, anti-mullerian hormone, antral follicle count, pregnancy
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