Home|Journals|Articles by Year|Audio Abstracts RSS - TOC

Original Article

Validation Study of c.746A>G SNP of BMPR1B Gene Associated with Litter Size in Sheep Genetic Resources of Bangladesh

Sabrina Islam Mony, Tanvir Mohammad Maruf, Nure Hasni Desha, Mohammad Hasanuzzaman Pabitra, Sadek Ahmed, Md. Munir Hossain, Mohammad Shamsul Alam Bhuiyan.


The BMPR1B gene is one of the major fecundity genes that have been investigated in different sheep populations worldwide for its association with prolificacy traits. The present study was performed to validate the association of c.746A>G SNP of BMPR1B gene with litter size trait in different sheep populations of Bangladesh. A total of 192 blood samples were collected from ewes of both farmers’ and institutional flocks comprising sheep populations of Jamuna River Basin (JRB), Barendra (BAT), Coastal (COR), Garole (GAR) and Muzaffarnagari (MUZ). Genotyping of the individuals was performed using PCR-RFLP method and single marker association analysis was carried out to evaluate the relationships between resultant genotypes and litter size trait using agricolae and pastecs packages of R software. The prolificacy attributed homozygous FecBBB genotype frequencies were 66, 50 and 55%, respectively in JRB, BAT and GAR populations whereas it was only 0-2% in MUZ and COR populations. Association analysis revealed highly significant (PG SNP that could be applied in marker assisted selection (MAS) program for identifying high prolific ewes in order to improve litter size trait at the population level

Key words: SNP, BMPR1B, Sheep, Prolificacy, Bangladesh

Full-text options

Share this Article

Online Article Submission
• ejmanager.com

ejPort - eJManager.com
Review(er)s Central
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.