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Candidiasis in HIV and AIDS Patients Attending the Nylon Health District Hospital in Douala, Cameroon

Anna Longdoh Njunda, Dickson Shey Nsagha, Jules Clement Ngeudia Assob, Henri Lucien Fouamno Kamga, Pride Teyim.


Abstract

AIM: Candidiasis is the leading opportunistic mycosis in HIV and AIDS patients.
METHOD: In order to determine its prevalence in patients with different CD4+ T cell categories in the Nylon Health District in Douala, a cross-sectional study was carried out whereby 304 HIV positive individuals were recruited between March and August, 2007. They were divided into two groups; those on highly active antiretroviral therapy (HAART) and those not on HAART. Three samples constituting mouth, vaginal/urethral swabs and urine were collected from each subject.
RESULTS: A total of 204 (67.1%) [95% confidence interval (CI): 0.618-0.724] of these patients had more than one predisposing condition to candidiasis, with those on antibiotic therapy having the highest prevalence (63.7%) followed by pregnant patients (7.3%) (P < 0.05). Candidiasis was more common in patients with low CD4+ T cell count (

Key words: HIV, AIDS, Candida albicans, opportunistic infection, CD4+ T cells, HAART

Article Language: Turkish English






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