Generalized pustular psoriasis (GPP) of von Zumbusch is a unique and rare type of psoriasis. The severe inflammatory skin disease has been postulated of having its relation to immunogenetics and exacerbated by various factors. Most GPP cases are sporadic, characterized by cutaneous manifestations of severe erythroderma, scaling skin, the lake of pustules, and may be accompanied by extracutaneous manifestations, including acute respiratory distress syndrome, heart failure, and sepsis. This investigation reported GPP in an elderly man with prior untreated psoriasis vulgaris and pneumonia, which, to our knowledge, was the first case in our secondary regential hospital, Bangli Medika Canti Hospital. The patient underwent systemic and topical corticosteroid therapy, intravenous ceftriaxone, wound dressing, and moisturizer, which yielded a satisfactory result. We present a case and literature review of this distinct phenomenon.
Key words: generalized pustular psoriasis, von Zumbusch, corticosteroid, wound dressing, therapy