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Original Article

ECB. 2014; 3(8): 850-854


C-BENZOTRAZOLATED NITRONES AS USEFUL SYNTHONS FOR THE SYNTHESIS OF 2,3-DISUBSTITUTED ISOXAZOL-5- ONES

Khalid Widyan.



Abstract
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A new and general method for preparation of C-benzotriazolated nitrones is reported. The reactivity of C-benzotriazolated nitrones is
applied for reaction with Reformatsky reagent in the absence of Lewis acid to produce 2,3-Disubstituted isoxazol-5-ones in good yields.

Key words: Synthesis, Diaryl(heteroaryl) nitrones, C-benzotriazolated nitrones, isoxazol-5-ones, Reformatsky reagent.





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