Cholesteatoma leads to hearing loss and various complications by causing bone erosion in the middle ear and mastoid in chronic otitis media (COM) patients. The mean platelet volume (MPV), neutrophil-lymphocyte ratio (NLR) and hematological parameters are proinflammatory markers. The purpose of this study is to compare the MPV, NLR and other hematological parameters of chronic otitis patients with and without cholesteatoma. It was planned to retrospectively assess the blood values of inpatients receiving chronic otitis surgery in the period of 2019-2020. Those who received tympanomastoidectomy due to COM with cholesteatoma were in one group, while another group consisted of COM patients without cholesteatoma who received only tympanoplasty. Each group contained 100 individuals. Our study aimed to investigate the relationship of these groups with hemoglobin, neutrophil, platelet, NLR and MPV values. There was a statistically significant difference between the tympanoplasty group and the cholesteatoma group in terms of age, neutrophil and MPV values (p
Key words: Tympanoplasty, mean platelet volume , cholesteatoma
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