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Original Article

ECB. 2014; 3(8): 792-797


SYNTHESIS AND ANTI-MICROBIAL ACTIVITIES OF SOME THIOUREA BASED METAL COMPLEXES

Vinayak S. Sonnekar, Wamanrao N. Jadhav, Satish A. Dake, Swapanil G. Dhole, Shankar S. Narwade, Rajendra P. Pawar.


Abstract

The transition metal (II) complexes were formed by the reaction of Co(II), Ni(II), Zn(II), Fe(II) and Cu(II) nitrates with the Schiff base
ligands. The complexes were characterized using infrared (FT-IR), electronic spectral (UV), elemental analysis, melting points and XRD
analysis etc. The transition metal(II) complexes were screened for antibacterial and antifungal activities. Antibacterial activity against four
bacteria such as Escherichia coli, Salmonella typhi, Staphylococcus aureus and Bacillus subtilis bacterial strains by the agar-cup method.
Antifungal activity was studied against four bacteria Aspergillus Niger, Penicillium Chrysogenum, fusarium moneliforme and aspergillus
flavus bacterial strains by the poison plate method. The complexes were found to exhibit higher to moderate activity against some bacterial
species.

Key words: Antibacterial activity; antifungal activity; metal complex; Schiff bases; FT-IR and UV-VIS spectral data.






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