Some new fused heterocyclic systems such as 1,2,4-triazolo[3,4-b]1,3,4-thiadiazoles and 1,3,4-thiadiazines were synthesized through the
reaction of the starting material 4-(4-amino-5-mercapto-4H-1,2,4-triazol-3-yl)phthalazin-1(2H)-one with triethyl orthoformate, furoyl
chloride, thiophene-2-aldehyde, phenylisothiocyanate, chloroacetonitrile, and p-nitro-2-bromoacetophenone. Also spiro systems were
achieved from reaction of the starting compound with isatine, and fluorenone. The newly synthesized 1,3,4-thiadiazoles and 1,3,4-
thiadiazines were obtained in good yields and their structures were elucidated by spectral data and elemental analysis.
Key words: triazolothiadiazole; triazolothiadiazine; spiro thiadiazole derivatives; phthalazin-1(2H)-ones; 4-amino-5-mercapto-1,2,4-
triazoles.
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