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Antioxidant and antihyperlipidemic effects of aqueous seed extract of Daucus carota L. in triton ×100-induced hyperlipidemic miceHabibu Tijjani, Abubakar Mohammed, Sani Muktar, Saminu Musa, Yusuf Abubakar, Adegbenro Peter Adegunloye, Ahmed Adebayo Ishola, Enoch Banbilbwa Joel, Carrol Domkat Luka, Adamu Jibril Alhassan. Abstract | | | Cited by 8 Articles | Daucus carota (carrot) seed is used traditionally in the treatment of diabetes mellitus, in which oxidative stress and hyperlipidemia are associated complications. The study evaluated the antioxidant and anti-hyperlipidemic effects of aqueous seed extract of Daucus carota (AQEDCS) in triton X100-induced hyperlipidemic mice. The in vitro antioxidant activities of the extract (0.21.0 mg/ml) was evaluated using 2,2-diphenyl-1-picrylhydrazyl, total antioxidant capacity, nitric oxide and ferric ion scavenging. In vivo antioxidant and anti-hyperlipidemic properties of the extract were evaluated using triton X100 induced oxidative stress and hyperlipidemia in mice. AQEDCS contains alkaloids, tannins, phenols and produced significant anti-oxidant effects in vitro compared to vitamin C. AQEDCS significantly (p
Key words: Daucus carota; Antioxidant; Seed; Anti-hyperlipidemia; Oxidative stress
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