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Original Article

ECB. 2014; 3(7): 624-626


AN EFFICIENT SYNTHESIS OF SOME NOVEL 5,7- DIARYLPYRIDO[4,3-d]PYRIMIDINES

V. Vijayakumar, P. Karthikeyan, S. Sarveswari.


Abstract

The 4-oxo-N,2,6-triphenylpiperidine-3-carboxamides (3a-f) were synthesized using arylaldehydes, ammonium acetate and acetoacetanilide,
which in turn converted into 5,6,7,8-tetrahydro-4-hydroxy-5,7-diarylpyrido[4,3-d]pyrimidin-2(3H)-ones (4a-f), 2-amino-5,6,7,8-tetrahydro5,7-diarylpyrido[4,3-d]pyrimidin-4-ols (5a-f) by condensing with guanidine carbonate and urea respectively

Key words: Synthesis; 4-oxo-N, 2, 6-triphenylpiperidine-3-carboxamides, 5,6,7,8-tetrahydro-4-hydroxy-5,7-diarylpyrido[4,3-d]pyrimidin2(3H)-ones, 2-amino-5,6,7,8-tetrahydro-5,7-diarylpyrido[4,3-d]pyrimidin-4-ols.






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