Abstract

The synthesis of pyrazoles and pyrimidines can be achieved from different chalcones using microwave irradiation within 5-8 min. Pyrazole and pyrimidine are nitrogen containing heterocyclic rings which are versatile lead compound for designing potent bioactive agents. The structures of the products were supported by IR, 1H NMR, 13C NMR and mass spectral data. The synthesized compounds showed a good antibacterial and antifungal activity

Key words: microwave irradiation; pyrazole; pyrimidines; antimicrobial activity