Abstract

Green synthesis of novel compounds 4-(2-carboxybenzamido)-2-hydroxybenzoic acids 3a-3e and 4-(1,3-dioxoisoindolin-2-yl)-2-hydroxybenzoic acids 4a-4e have been developed in good yields which were analogues of p-aminosalicylic acid (used as anti-tuberculosis agent).

Key words: phthalic anhydrides; p-aminosalicylic acid; anti-tuberculosis agents; 4-(2-carboxybenzamido)-2-hydroxybenzoic acids; 4-(1,3-dioxoisoindolin-2-yl)-2-hydroxybenzoic acids