Home|Journals|Articles by Year|Audio Abstracts
 

Original Article

ECB. 2014; 3(5): 452-456


CRYSTAL STRUCTURES AND STABILITY OF HYDRATES AND DEUTERIOHYDRATES OF QUINOLINE N-OXIDES

Vladimir P. Andreev, Dmitry O. Zaitsev, Yurii A. Velikodny, Vladimir V. Chernyshev.




Abstract

The protiated (H2O) and deuteriated (D2O) crystallohydrates of quinoline N-oxide, 2-methylquinoline N-oxide and 4-methylquinoline Noxide demonstrate different behavior at ambient conditions, namely, the deuteriated dihydrates undergo solid state transformation into crystalline anhydrous or hemihydrate forms, while protiated dihydrates loss 3D periodicity. In attempts to explain this phenomenon, the crystal structures of the six compounds – namely, quinoline N-oxide and quinoline N-oxide dihydrate, 2-methylquinoline N-oxide hemideuteriohydrate and 4-methylquinoline N-oxide dihydrate, 4-methylquinoline N-oxide and 4-methylquinoline N-oxide dihydrate – were analyzed.

Key words: quinoline N-oxide; 2-methylquinoline-N-oxide; 4-methylquinoline-N-oxide; crystallohydrates ; deuteriohydrates; dehydration, crystal structure; powder X-ray diffraction






Full-text options


Share this Article


Online Article Submission
• ejmanager.com




ejPort - eJManager.com
Refer & Earn
JournalList
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under Creative Commons Attribution 4.0 International License (CC BY), which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.