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Correlation between serum uric acid level with obesity indices and blood pressure in young males

Saira Bano, Anuradha Rajiv Joshi, Savita M Vaidya.




Abstract

Background: Hyperuricemia is associated with lifestyle diseases such as hypertension and obesity. Studies have shown a positive association of obesity with uric acid and hyperuricemia causes endothelial injury resulting in hypertension. The prevalence of obesity is increasing in young adults.

Aims and Objectives: The present study was planned to correlate serum uric acid (SUA) level with blood pressure to reflect the effect of hyperuricemia on hypertension. SUA level was also correlated with various obesity indices to indicate that these simple indices may be sufficient to predict raised uric acid level.

Materials and Methods: The study was approved by the institutional ethical committee. The study group consisted of 74 males of 19–35 years of age. SUA level was estimated by modified Trinder’s peroxide method. Blood pressure, body mass index (BMI), waist circumference (WC), waist-to-hip ratio (WHR), and waist-to-height ratio (WHtR) were measured as per the WHO protocol. Data were analyzed by Pearson correlation coefficient. Multiple regression analysis was done to determine independent predictor of SUA.

Results: There was a statistically significant positive correlation

Key words: Obesity Indices; Blood Pressure; Waist-to-hip Ratio; Body mass index






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