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BK virus incidence, risk factors and its effect on mortality in hematopoietic stem cell transplant patients-single center experience

Mehmet Veysi Deviren, Ahmet Sarici, Mehmet Ali Erkurt, Omer Faruk Bahcecioglu, Soykan Bicim, Ilhami Berber, Emin Kaya, Mustafa Ozgul, Irfan Kuku.




Abstract

The aim of this trial is to investigate the risk factors of BK viruria and the effect of BK viruria on mortality in patients undergoing hematopoietic stem cell transplantation (HSCT). The data of 247 patients who underwent HSCT between 01.01.2011-01.12.2017 in Inonu University Faculty of Medicine Department of Hematology were retrospectively analyzed. BK viruria was defined as positive at any copy level in the urine. Of 247 patients, 97 patients (39.2%) were detected to have BK virus-positive. Patients with positive BK virus in urine were younger than BK virus negative patients, and patients with multiple myeloma had a lower rate of BK virus positivity than other patients (p

Key words: BK virus, hematopoietic stem cell transplantation, busulfan, cyclophosphamide, mortality






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