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Quinolone Arthropathy in Broiler Chicken Administered with Enrofloxacin

Veerapandian Sureshkumar, Ghadevaru Sarathchandra.

Arthropathic potential of enrofloxacin was investigated in broiler chicken at recommended therapeutic dose. Day old broiler chicks were randomly divided into 4 groups each comprising 6 birds. Group I, control birds received non medicated water, while group II, III, IV and V were medicated with enrofloxacin at recommended therapeutic dose 10mg/Kg body weight in drinking water for 5 successive days from 43rd to 47th day of age. Juvenile cartilages were collected on 1, 3, 5 and 9 days after the last dose from respective treatment groups and subjected to histopathological examination. Degeneration of chondrocytes was noticed in day 1 post treatment group and shrunken chondrocytes with pyknotic nuclei were observed till 5th day post treatment. However, clumping of chondrocytes observed on day 5 post treatment and a few cases of degenerated chondrocytes on day 9 post treatment around the blood vessels, suggestive of reversal in chondrocyte lesions.

Key words: Enrofloxacin, Arthropathy, Juvenile Cartilages, Broiler Chicken

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Journal of Complementary Medicine Research


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