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Research Article

JCDR. 2021; 12(6): 1255-1258


ASSOCIATION OF VITAMIN D STATUS WITH SEVERITY OF COVID 19

Manoj Kumar,VidyaSagar Ram,Pankaj Kumar,Shushil Kumar Yadav.


Abstract

Background:The present study was undertaken for assessing the association of serum vitamin D level
with severity grading in COVID 19 RT-PCR positive patients. Materials & methods: 50 Patients
diagnosed to have COVID 19 infection above age of 18 years admitted in COVID positive ward and
COVID positive ICU were enrolled. Complete demographic and clinical details of all the patients were
recorded. Serum vitamin D levels were assessed using auto-analyser and were correlated with severity
of COVID-19. All the results were recorded in Microsoft excel sheet and were analysed by SPSS
software. Results:Mean serum vitamin D levels among patients with mild, moderate, severe and
critically ill COVID-19 was 33.4 ng/mL, 28.2 ng/mL, 23.2 ng/mL and 19.5 ng/mL respectively.
Significant results were obtained while comparing mean serum Vitamin D levels among different
severity of COVID-19. Conclusion:The overlap in the vitamin D associated biological pathways with
the dysregulation reported to drive COVID-19 outcomes warrants further investigation, as does the role
that vitamin D levels at time of presentation of COVID-19 may have as predictive biomarkers of
disease severity.

Key words: COVID-19, Vitamin D






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