Home|Journals|Articles by Year

Directory for Medical Articles
 

Review Article

SRP. 2021; 12(3): 96-99


Estimation Of Plasminogen Activator Inhibitor -1 And Some Biochemical Markers In A Sample Of Iraqi Patients With Liver Cirrhosis

Wassan Abdul Kareem, Baydaa Hameed Abdullah, Huda Jaber Waheed.


Abstract

Objective: The aim of present study was designed to estimate level of plasminogen activator inhibitor -1 in liver cirrhotic patients, and its correlation with some biomarkers includes ( Liver enzymes: ALT,AST and Bilirubin ,Total protein, albumin. Methods: The current study include 30 Iraqi liver cirrhotic patients with age range 25-65 years and 30 healthy control subjects with age range 25-60 years. Results: The present study had been shown a high significant differences in liver enzymes ALT, AST and ALP when compare with control p≤ 0.01, 0.05 and 0.01 respectively. The difference in the mean serum level of albumin and total bilirubin were also observed to be highly significant in the liver cirrhosis patients p ≤ 0.01. Concerning mean serum level of PAI-1 in the liver cirrhosis patients a significant deference was found when compared to control with p≤0.05. Also there were a non-significant correlation between age and studied parameters Conclusions: The results of the present study showed a significant increase in serum levels of PAI-1 ALT,AST,ALP,T Bilirubin ,and Albumin while a non-significant differences in these parameters was shown in relation to age and gender.

Key words: liver cirrhosis, plasminogen activator inhibitor -1






Full-text options


Share this Article



Online Article Submission
• ejmanager.com







eJManager.com
Review(er)s Central
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.