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Original Article



EFFECT OF ETHANOLIC SEED EXTRACT OF CAESALPINIA BONDUCELLA ON HORMONES IN MIFEPRISTONE INDUCED PCOS RATS

Balasubramanian Meera Murugesan, Palayyan Muralidharan, Rajeswary Hari.




Abstract
Cited by 23 Articles

The aim of the current study is to evaluate the effect of ethanolic seed extract of Caesalpinia bonduella (ESECB) on altered hormonal levels in mifebristone induced PCOS female rats. PCOS was induced in female rats by a daily administration of mifepristone (4mg/kg b.w.) for 8 days which was confirmed by the persistent estrous cycle. Once PCOS was induced the rats were treated with ethanolic seed extract of Caesalpinia bonducella (ESECB) 200mg and 400mg/kg b.w. p.o. for 28 days, and the hormonal parameters were analyzed. Metformin was used as a standard drug. A significant increase (p

Key words: Caesalpinia bonducella, ESECB, PCOS and Mifepristone






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