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Clinical and hematological findings in patients with coronavirus disease (COVID-19): Review

Winnie Pratiwi Achmad, Rahmawati Minhajat.

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Coronavirus Disease 2019 (COVID-19) is a new type of disease that humans have never previously identified. The virus that causes COVID-19 is called SARS-CoV-2. In humans, SARS-CoV-2 primarily infects cells and glycoproteins contained in the envelope spike of the virus will bind to the ACE2 cellular receptor. The clinical manifestations of COVID-19 patients have a broad spectrum, ranging from asymptomatic to mild to severe. This disease significantly affects the haematological system and hemostasis, so haematological findings play an important role in screening and as a prognostic marker. Lymphopenia, thrombocytopenia, leukocytosis, and neutrophilia are important laboratory findings. Several other haematological and hemostasis parameters were found, including neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR), lymphocyte to monocyte (LMR), and absolute lymphocyte count (ALC).

Key words: Covid-19, Hematological finding, Clinical finding

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