|ECB. 2019; 8(12): 405-408
SYNTHESIS OF 1H-INDAZOLES USING LEMON PEEL POWDER AS A NATURAL, GREEN AND EFFICIENT CATALYST UNDER ULTRASOUND IRRADIATION
Swati S. Ghodke, Priya M. Khandare, Sadhana N. Salve, Pravin S. Kendrekar, Dhanaji Rajani, Rajendra P. Pawar.
Bioactive 1H-indazoles were synthesized from 2-substituted aromatic aldehydes and hydrazine hydrate using DMSO and lemon peel powder as a green and efficient natural catalyst. In comparison to other reported conventional methods, this method affords good yield under ultrasonic irradiation.
Key words: 2-substituted aldehydes, 1H-indazoles, hydrazine hydrate, natural catalyst, lemon peel powder (LPP).