A CONVENIENT CATALYST-FREE SYNTHESIS OF SOME SUBSTITUTED PYRIDINE BENZAMIDES FROM ARYL ALDEHYDES
Vaishanavi S. Jambhorkar, Aniket P. Sarkate, Aishwarya P. Rajhans, Kshipra S. Karnik, Sajed H. Ansari, Shambala U. Chavan, Yogesh W. More, Dattatraya N. Pansare.
A new method of amides synthesis under catalyst-free condition has been developed by using aldehydes and aminopyridines. The amides were synthesized by using different aldehydes and aminopyridines using ethanol as a solvent and hydrogen peroxide as oxidant. The method helps in preparation of amides which were acquired in good yield within 4-5 h using conventional heating. The reaction is catalystfree. The developed method is easy, economical, and flexible.
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