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Topically Applied Tetrapleura tetraptera Stem-Bark Extract Promotes Healing of Excision and Incision Wounds in Rats

David Emery Tsala, Solomon Habtemariam, Foyet Harquin Simplice, Martin Thierry Bella Ndzana, Abraham Abraham Jital, Theophile Dimo.



Abstract
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Objective. The objective of the present study was to evaluate the in vivo wound healing effect of water extract of Tetrapleura tetraptera in stem-bark. Method: The healing activity was studied in 40 male rats using excision and incision wounds on normal and dexamethasone-suppressed wound healing. For each model, rats were divided in 4 groups as follows: control, dexamethasone, T. tetraptera and dexamethasone combined with T. tetraptera. Results: Data recorded exhibited a significant effect by the extract in the epithelialization time within 14 and 18 days of the normal and dexamethasone-induced healing delay rats respectively (p

Key words: Tetrapleura tetraptera, skin, excision wound, incision wound, epithelialization, tensile strength

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010203040506070809101112
2025

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