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Research Article

ECB. 2019; 8(6): 176-179


ONE POT BF3.MeCN CATALYZED SOLVENT FREE SYNTHESIS OF 3,4-DIHYDROPYRIMIDINE-2-ONE ANALOGUES

Ajit A. Kharpe, Tukaram S. Choudhare, Santosh N. Mokale, Prashant D. Netankar.




Abstract
Cited by (1)

One-pot solvent free three components coupling of aryl aldehydes, β-dicarbonyl compounds, urea or thiourea was performed to afford corresponding 3,4-dihydropyrimidine-2-ones and their sulfur analogs 3,4-dihydro-pyrimidine-2-thiones. It is the first report of BF3.ACN catalyzed the solvent-free synthesis of pyrimidone analogs.

Key words: BF3.ACN, solvent-free, 3,4-dihydropyrimidine-2-one






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