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Research Article

ECB. 2020; 9(8): 196-198


ONE-POT SYNTHESIS OF 1,2,4-TRIAZINE DERIVATIVES OF 2-SUBSTITUTED BENZAMIDES IN [BMIM][OH]

V. Anitha Rani, Y. Bharathi Kumari.


Abstract

One-pot three component synthesis of (Z)-N-5-(benzylidene/substituted benzylidene)-3-methyl-6-oxo-1,2,5,6-tetrahydro-1,2,4-triazine-2-substituted benzamide derivatives were described by one-pot reaction of (Z)-4-(benzylidene/substituted benzylidene)-2-methyl-oxazol5(4H)-ones with hydrazine hydrate followed by PhCH=NPh in [BMIM][OH] as ionic liquid for 30 min at 80-85 oC. The importance of this method includes shorter reaction time and high yield.

Key words: One-pot synthesis, Schiff bases, [BMIM][OH], 1, 2, 4-triazine.






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