A clean and straightforward methodology developed for the synthesis of substituted indazoles using silica supported polyphosphoric acid
(PPA-SiO2) catalyzed condensation reaction between substituted 2-hydroxybenzaldehydes or acetophenones and hydrazine hydrate or
phenylhydrazine. The reaction conditions are optimized for different solvents at different temperatures. The yield of the products improved
to 88 to 90 % using silica supported polyphosphoric acid as a catalyst, which is reusable, cost-effective and straightforward to synthesize.
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