Home|Journals|Articles by Year

Directory for Medical Articles

Short Communication

Production of a Healthy Farm-Born Calf by Modified Somatic Cell Nuclear Transfer

Andrew W Taylor-Robinson, Simon Walton, Gábor Vajta.

Cited by (1)

The primary intention of somatic cell nuclear transfer in cattle is commercially driven, notably to generate genetically superior animals with desired phenotypic traits as breeding stock. The widespread application of bovine cloning has been hampered by technical difficulties to which recently introduced zona pellucida-free procedures may offer a solution. The most radical approach is so-called ‘handmade cloning’ which does not require micromanipulators because enucleation and nucleus transfer are both performed manually. Handmade cloning is a rapid and efficient technique that requires less expertise and time than traditional nuclear transfer methods and the cost of equipment is significantly less. Here, we report the birth of the first farm-born calf from a modified handmade cloning process, with success achieved at only the second attempt. While caution is warranted, this represents potentially the first viable cloning method for large-scale improvement of cattle breeding.

Key words: Embryology, In vitro fertilization, Cloning, Reproduction, Cattle.

Full-text options

Share this Article

Online Article Submission
• ejmanager.com
• ojshosting.net

Do you want to use OJS for your journal ?
work with an experienced partner

Review(er)s Central
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.