Abstract

Background: An efficient pharmacovigilance (Pv) system of any country improves patient care and safety. Lack of awareness among health-care professionals (HCPs) is cited as one of the main reasons along with underreporting of adverse drug reactions (ADRs). Knowledge, attitude, and practice (KAP) studies can help understand various issues and improve Pv system. Hence, this study was designed to assess the KAP of the HCPs in a tertiary care hospital and also to explore reasons for underreporting of ADRs.

Aim and Objective: The aim of the study was to evaluate the KAP of the HCPs in a tertiary care hospital and also to explore reasons for underreporting of ADRs.

Materials and Methods: A cross-sectional self-administered questionnaire-based study was conducted among 500 HCPs. A pre-validated questionnaire was used containing a total of 20 questions about KAPs toward Pv along with one question to identify the reasons for underreporting of ADRs. Data obtained were analyzed using descriptive statistics.

Results: About 59.6% knew what is the definition of Pv. About 63% had knowledge on existence of national Pv program in India. A significant number of participants (>70%) felt that there should be an ADR monitoring center in every hospital and also that its necessary to report ADRs. Even though, more than >60% participants had undergone training in Pv and had experienced ADR in their professional practice only 39.6% of participants reported an ADR. Lack of time (43.4%) was found to be the single most important reasons for under-reporting.

Conclusion: Most of the participants did realize the importance of Pv system but were lacking in practice. Hence, regular awareness program and training in ADR reporting could help in bridging this gap.

Key words: Pharmacovigilance; Knowledge, Attitude and Practice; Health-Care Professionals; Under-reporting