Home|Journals|Articles by Year|Audio Abstracts
 

Research Article

ECB. 2018; 7(4): 162-167


LOWBUSH BLUEBERRY EXTRACT PROTECTS NORMAL HUMAN (HOMO SAPIENS L.) EPIDERMAL KERATINOCYTES FROM DAMAGE BY UV-B IRRADIATION

Seiji Yamasaki,Kenji Mizoguchi,Naohiro Kodama,Joji Iseki.




Abstract

To search for natural materials that protect human skin from damage caused by ultraviolet-B (UV-B) irradiation, we prepared water extracts of the following four dry berries: lowbush blueberry (LBB) (Vaccinium angustifolium L.), highbush blueberry (HBB) (Vaccinium corymbosum L.), cranberry (CB) (Vaccinium macrocarpon Ait.) and grape (Vitis vinifera L.). Normal human epidermal keratinocytes (NHEKs) were pretreated with each of the extracts and then subjected to transient UV-B irradiation (15.0 W m-2) for 80 s. The results showed that pretreatment of NHEKs with LBB extract significantly attenuated UV-B-induced damage. The concentrations of proanthocyanidins, total flavonoids and total polyphenols in LBB extract were higher than those in the other three berry extracts. Therefore, these compounds might mediate the protection of NHEKs from UV-B-induced damage.

Key words: flavonoids, normal human epidermal keratinocytes (NHEKs), polyphenols, proanthocyanidins, ultraviolet-B (UV-B).






Full-text options


Share this Article


Online Article Submission
• ejmanager.com




ejPort - eJManager.com
Refer & Earn
JournalList
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under Creative Commons Attribution 4.0 International License (CC BY), which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.