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Review Article

tjtfp. 2022; 13(4): 182-192


PARKİNSON HASTALIĞI ve PARKİNSONİZM

Tuba Erdoğan Soyukibar, Dilaver Kaya.



Abstract
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Abstract
Parkinson’s disease (PD), or paralysis agitans is a common neurodegenerative and heterogeneous disorder. Parkinson's symptoms include bradykinesia, rigidity and tremor. PD is pathologically characterized by the loss of dopaminergic neurons of the substantia nigra. Treatment involves pharmacologic and nonpharmacologic approaches.
Abstrakt
Parkinson hastalığı paralizi ajitans olarak da bilinen sık görülen nörodejeneratif ve heterojen bir hastalıktır. Semptomlar arasında bradikinezi, rijidite ve tremor vardır. Hastalığın karakteristik patolojik özelliği, substansiya nigrada dopaminerjik nöronal kayıp olmasıdır. Tedavide hem farmakolojik hem de farmakolojik olmayan yöntemler bulunmaktadır.

Key words: Parkinson hastalığı, Parkinsonizm, Tedavi, Ayırıcı tanı





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