Home|Journals|Articles by Year

Directory for Medical Articles
 

Research Article

ECB. 2017; 6(12): 554-557


EFFECT OF HYDROALCOHOLIC EXTRACT OF CAPPARIS DECIDUA (FORSSK.) EDGEW ON SERUM TESTOSTERONE AND SPERMATOGENESIS IN RATS

Prashant Kumar Dhakad, Pramod Kumar Sharma, Sokindra Kumar.


Abstract

The effect of Capparis decidua(Forssk.)Edgew aqueous extract on the Wistar rat testes was investigated with a view to evaluating the pharmacological basis for the use of Capparis decidua hydroalcoholic extract as an aphrodisiac. Wistar rats were divided in the following experimental groups- control group (1 mL kg-1), sildenafil citrate treated (5 mg kg-1), C. decidua (100 mg kg-1), C. decidua (200 mg kg-1), per se group (only C. decidua 200 mg kg-1). The hydroalcoholic extract of root, stem & leaves of C. decidua was studied for their effect on the body and secondary sexual organ weight, spermatogenesis, and serum testosterone level male rats. The animals were allowed free access to drinking solution during the 28 days period of exposure. At the end of the experimental period, rats were sacrificed, testis, epididymis, seminal vesicles and prostate glands were excised and weighed, and serum testosterone level was recorded. The testesunderwent histological examination. Oral administration of the extract in Wistar rats showed significant dose-dependent influence on serum testosterone level (P

Key words: Capparis decidua, aphrodisiac, serum testosterone level, body weight, secondary sexual organ weight.






Full-text options


Share this Article



Online Article Submission
• ejmanager.com







eJManager.com
Review(er)s Central
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.