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NMJ. 2013; 2(2): 93-106

Title: A comparative study of memory boosting and regaining effect of oral administration of cardamom and cinnamon in wistar albino rats.

Sai Sailesh kumar, Prabha V Setty, Joseph Kurien Mukkadan.

Background and objectives: Although a few drugs are available today for the management of Alzheimer’s disease (AD) and many plants and their extracts are extensively employed in animal studies and AD patients, yet no substantial drug or plant extract is able to reverse the AD symptoms adequately. It is tangible that there has been augmenting needed for such therapeutic intervention. The present study was undertaken with an objective to compare the memory boosting and regaining effects of oral administration of cinnamon and cardamom which are used commonly as spice in various dishes.
Materials and Methods: A total of 36 male and female wistar albino rats were used for this study. They were randomly assigned into three groups with 8 rats in each group. The influence of oral intake of cinnamon and cardamom extract on behavioral task performance was studied by using T-maze and radial arm maze and physiological measures relative to a milk control group was investigated.
Results: We have observed significant memory boosting and memory regaining effects of cinnamon when administered orally. However, cinnamon is having strong memory regaining effect than cardamom.
Conclusion: We conclude that cinnamon is having strong memory regaining effect than cardamom. However further pharmacological and biochemical investigations will clearly elucidate the mechanism of action and helpful in projecting these plant extracts as a therapeutic target in Alzheimer’s treatment.

Key words: Key words: Memory boosting, Memory retention, Cardamom extract, Cinnamon extract.

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