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Antioxidant and Antidiabetic Activity of Ethanolic Extract of Terminalia Chebula

S. Kesava priya, T. Lakshmi, Anitha Roy, S. Rajeshkumar.


Abstract

Primary antioxidants directly scavenge free radicals, while secondary antioxidants indirectly prevent the development of
free radicals through Fenton’s reaction. Antioxidant activity is characterised as “a limitation of the oxidation of proteins,
lipids, DNA, or other molecules that occurs by blocking the propagation stage in oxidative chain reactions.”Phytochemical
screening of both extracts indicated the presence of phenolic compounds, flavonoids, saponins, tannins, and steroids,
which might contribute to the antidiabetic activity. The research is needed to find whether the ethanolic extract of
terminalia chebula has antioxidant and antidiabetic activity. The research also fulfils the deficiency of work on comparing
its antioxidant and antidiabetic activity of terminalia chebula to compare with its standards.The aim of the research is
to find the antidiabetic and antioxidant activity of ethanolic extract of terminalia chebula. The methodology adopted in
this study was DPPH assay. For antidiabetic activity a total of 5 concentrations of ethanolic extract of terminalia chebula
was prepared and compared with the standard and for antioxidant activity a total of 5 concentrations was compared to
the standard. From the results both shows when the concentration increases the percentage of inhibition also increases
when compared to standard in antioxidant activity and antidiabetic activity when concentration increases the percentage
of inhibition also increases when compared to standard.

Key words: erminalia chebula, antioxidant activity, antidiabetic activity, ethanolic extract.






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