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Case Report

SETB. 2011; 45(3): 98-101

An important side effect of lamotrigin use: combined of Stevens johnson syndrome and toxic epidermal necrolysis

İhsan Kafadar, Betül Diler, Nazan Dalgıç Karabulut, Özlem Haşim.


Stevens-Johnson syndrome is a rare, potentially life-threatening syndrome that occurs two months after exposure to anticonvulsants drugs such as phenobarbital, phenytoin, carbamazepine and lamotrigine. The use of the offending drug must be terminates immediately to prevent potentially fatal outcomes. In this study, we report a patient diagnosed generalized seizures, and who had received Lamotrigine but developed generalized skin rash at the second week of treatment and the drug was stopped.

Key words: Lamotrigine, Stevens-Johnson syndrome, skin rash

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