Abstract

Distal renal tubular acidosis (dRTA) is a genetic disease characterized by metabolic acidosis, alkaline urine, hypokalemia or hyperkalemia, and hypercalciuria. Clinically develpomental delay signs are polyuria, dehydration, vomiting, and psychomotor retardation with hypotonia may be seen. Nephrocalcinosis and urolithiasis are among the complications of hypercalciuria which may lead to renal failure.. A three days old newborn was admitted with complaints of fever and fatigue. The blood gas analysis revealed: pH: 6.89, PCO2: 32.8, PO2: 40.7, HCO3: 6.2, BD: - 2.26. Anion gap was normal. Urine pH was 7. In urinary ultrasonography, grade 2-3 nephrocalsinosis was observed. Right sided hearing loss was found in BAER test. By this way, the early diagnosis and treatment of RTA cases may be possible.When metabolic acidosis is encountered in a neonate during the first days of life after birth, serum electrolyte values,anion gap and urine pH should be determineted.

Key words: Distal renal tubular acidosis, metabolic acidosis, newborn