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Original Research

SETB. 2010; 44(3): 100-105

Common skin findings in children with acute leukemia

Eylem Ceren, Gonca Gökdemir, Zeynep Yıldız Yıldırmak, Adem Köşlü.


Aim: Leukemias are the most common malignancies in childhood with a proportion of %25-40. Manifestations of the skin findings can be a router. There are only a few researches in the literature about this subject. Our aim was to determine the skin findings in children with acute leukemia.

Materials and Methods: The cases who were treated and followed up in Pediatric Hematology and Oncology Clinics were included in the study. The diagnose and duration of the disease, whether in remission or not and patients’ treatment were noted. Dermatologic examination was recorded as a standard form.

Results: 59 acute leukemia patients (32 boys, 27 girls; aged 18 months to 17 years - mean:8.69 years) were included in the study. 6 of the patients were acute myeloblastic leukemia and 53 of them were acute lymphoblastic leukemia. Patients were seen 1-6 times (mean:2.30) and disease periods were 1 month to 8 years (mean:2.31 years). 89.8% of the patients were in remission (53/59: 31 boys, 22 girls). In the cases of 93.2%, skin lesions were observed at least one examination (except 1 acute myeloblastic leukemia and 3 acute lymphoblastic leukemia patients). Skin infiltration of acute leukemia was not found. Kserosis, diffuse alopecia, miliaria, purpura and pitriasis simplex were the most frequent dermatoses.

Conclusions: 93.2% of the patients were observed to have skin lesions. Nonspesific skin lesions were detected in the foreground. Although these results are compatible with similar publications, we believe that the studies done with extensive series can give more healthy results.

Key words: Acute leukemia, children, skin findings

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