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Original Research

SETB. 2010; 44(2): 66-71

Use of desflurane and sevoflurane for elective caesarean section: maternal and neonatal effects

A. Banu Burgutoğlu, Birsen Ekşioğlu, G. Ulufer Sivrikaya, Melahat K. Erol, Ayşe Hancı.


Objective: In our study we aimed to compare the maternal and neonatal effects of desflurane and sevoflurane in women undergoing elective caesarean section.

Methods: After the approval from Ethics Committee of our Hospital, 40 healthy parturients undergoing elective caserean section were allocated randomly into two groups after their informed consent was taken. Desflurane 3% in Group D or sevoflurane 1% in Group S were used in a 50% nitrous oxide and oxygen mixture for maintenance of anaesthesia. Systolic, diastolic, mean blood pressure, heart rate values and peripheral oxygen saturation were recorded as baseline and followed up with 5 min intervals peroperatively. Neonatal status was evaluated with APGAR scores at 1 and 5 min, umblical cord blood gas analysis, neurologic adaptive capacity scores at 2 and 24 h. Extubation and recovery times of the mother, haemoglobin and haematocrit values were recorded preoperatively and at postoperative 24.hours.

Results: Blood pressure and heart rate changes were similar in Group D and Group S in intraoperative period. Neonatal outcome was evaluated similar in Group D and Group S. Extubation and recovery times were shorter in Group D than Group S. Haemoglobin and haematocrit values were similar between the groups preoperatively and at postoperative 24 hours.

Conclusion: We concluded that; the maternal and newborn effects of desflurane and sevoflurane were similar, and desflurane can be preferred to sevoflurane with the conditions for early extubation and short recovery period in elective caesarean operations in the concentrations that we have used.

Key words: Caesarean section, sevoflurane, desflurane, newborn, APGAR

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