Home|Journals Follow on Twitter| Subscribe to List

Directory for Medical Articles

Open Access


SETB. 2012; 46(4): 170-180

Evaluation of carotid plaque morphology with magnetic resonance imaging (MRI)

Zeynep Tanrıverdi, Suzan Tunç, Ali Zeynel Tak, Dilek Necioğlu Örken, Ender Uysal, Muzaffer Başak.

Objective: Atherosclerosis at the carotid bifurcation is likely the major cause of ischemic stroke. Besides degree of stenosis, plaque characteristics are suggested to play a potentially important role as risk factors for stroke. The main aim of this study was to evaluate, morphological features such as intraplaque hemorrhage (IPH ), fibrous cap of the plaque with MRI.

Methods: A total of 23 patients with large artery atherosclerotic ischemic stroke were enrolled in this study. All underwent MRI assessment of the carotid arteries for intraplaque hemorrhage and fibrous cap rüpture. We compared plaque morphology with degree of stenosis.

Results: Mean± SD age of the patients was 60.7± 6.9 and 8 of 23 were female. Of the 11 symptomatic carotid arteries included, 5 had IPH and 5 had fibrous cap rupture. Non of the asymptomatic arteries had these pathologies. The relationship between degree of stenosis, IPH and fibrous cap rupture were not statistically significant (p= 0.63 and 0.25).

Conclusion: Besides the degree of stenosis, plaque characteristics are suggested to play a potentially important role as risk factors for stroke. MRI is well suited for evaluating carotid plaques; it is widely available, noninvasive, provides excellent soft tissue contrast, multiplanar imaging capability. In our study, we didn’t find a statistically significant relationship between degree of stenosis and plaque morphology but evaluation of patients with MRI provided additional information. More studies with larger patient groups are needed.

Key words: Atherosclerosis, intraplaque hemorrhage, fibrous cap rupture, plaque, magnetic resonance imaging (MRI)

Article Language: Turkish English

Share this Article

Journal of Complementary Medicine Research


BiblioMed Home
Follow ScopeMed on Twitter
Author Tools
eJPort Journal Hosting
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
ScopeMed is a Database Service for Scientific Publications. Copyright © ScopeMed® Information Services.