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Research Article

ECB. 2017; 6(5): 201-205


SYNTHESIS AND CHARACTERIZATION OF SOME 4-SUBSTITUTED THIAZOLIDINONE DERIVATIVES

Assala Salam Jebur, Mahmood Shakir Magtoof.


Abstract

This study is concerned with the synthesis and characterization of 4-thiazolidinone derivatives )3a-3h(. These compounds were prepared by reacting mercaptoacetic acid with the appropriate Schiff bases (imines) by heating at 50-60 °C in chloroform with moderate yields (51-75 %). The structures of these 4-thiazolidinone derivatives were established on the basis of the spectral studies using IR, 1H-NMR, 13CNMR, 13C-NMR DEPT and MS.

Key words: Thiazolidinones; imines; synthesis; NMR spectroscopy






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