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Natl J Med Res. 2013; 3(2): 162-165

Role of Platelet Parameters in Diagnosing Various Clinical Conditions

Amar R. Shah, Sanjay N. Chaudhari, Menka H. Shah.

Background: With improvement in the technologies, advancement occurs in all field including medicine. Automated cell counters are widely used for diagnosis of different diseases. Hematocrits are important parameters that are used in routine practices. Now a day for analysing platelet abnormalities, plateletcrits are utilized. Among them Platelet counts, mean platelet volume (MPV) and platelet distribution width (PDW) are important parameters.
Aims and objective: To study platelet parameters in various clinical conditions.
Materials and Methods: A cross sectional observational study was carried out at one of the rural teaching hospitals of Gujarat. Laboratory Data from 800 patients were analysed using Microsoft excel.
Result: Total 800 patients were enrolled in the study. Among them 384 (48%) were females and 416 (52%) were males. Maximum (47%) patients were of 15- 49 yrs age group. 228 (28.5 %) patients were having infectious diseases. Whereas 248 (31%) of patients have attended clinics with chronic diseases. Patients having illnesses related to haematological causes were 144 (18.0%). Significant increase in Platelet Distribution Width & Mean platelet volume was observed among Pregnant women. Thrombocytosis was found in cases of anemia. Significantly lower platelet count were observed in Acute Myeloid leukemia (AML) and Immunothrombocytopenic pupura (ITP). Patients with ITP were having high Mean platelet count and Platelet distribution width. Inverse relationship was observed between MPV and Platelet count in cases of Anaemia. Linear relationship was observed between MPV and Platelet count among patients of ITP.
Conclusion: Platelet parameters vary in different clinical conditions and they should be used routinely to aid in diagnosis.

Key words: Platelet count, Mean Platelet Volume, Platelet Distribution Width, Clinical conditions

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