The improved syntheses of 5-(indol-3-yl)-5-hydroxypyrimidine-2,4,6(1H,3H,5H)-trione (1), 5-(5-methylfuran-2-yl)-5-hydroxypyrimidine2,4,6(1H,3H,5H)-trione (2), 5-(5-N,N-dimethylhydrazonylfuran-2-yl)-5-hydroxypyrimidine-2,4,6(1H,3H,5H)-trione (3), 5-(4-N,N-dimethyl-aminophenyl)-5 hydroxypyrimidine-2,4,6(1H,3H,5H)-trione (4a), and 5-(4-N,N-diethylaminophenyl)-5-hydroxypyrimidine-2,4,6 (1H,3H,5H)-trione (4b) from alloxane in mild conditions were reported. The structure of 5-(indol-3-yl)-5-hydroxypyrimidine2,4,6(1H,3H,5H)-trione (1) has been determined by XRD study.
Key words: alloxan; indol; 2-methylfurane; 5-(indol-3-yl)-5-hydroxypyrimidine-2,4,6(1H,3H,5H)-trione; 5-(5-methylfuran-2-yl)-5-hydroxypyrimidine-2,4,6(1H,3H,5H)-trione; synthesis; structure
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