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Original Research

BTDMJB. 2007; 3(1): 10-14

Retrospective evaluation of 101 cases with Henoch-Schönlein purpura

Gülay Çiler Erdağ, Ayça Vitrinel, Gül Yeşiltepe, D Alper Gürsu, Turgut Ağzıkuru, Yasemin Akın.

Objective: The medical records of 101 children who had Henoch Schönlein Purpura (HSP), admitted to our clinic in the past 9 years were
reviewed retrospectively regarding clinical findings, laboratory values, etiological factors, complications and cases with atypical
Material and Methods: Between January1996 and April 2005, 101 patients were diagnosed as HSP in our clinic. Retrospective evaluation
of patient files was done regarding clinical findings, laboratory values, etiological factors, and complications.
Results: Among 101 patients diagnosed as HSP revealed palpable purpura (91%), arthralgia (54%), abdominal pain (46.5%), nausea and
vomiting (11.8%), fever (8.9%), scrotal edema (3.96%), macroscopic haematuria (3.96%) were the most common presenting symptoms. In 4
(3.96%) patients invagination occurred. 45 (44.5%) of the patients had renal involvement as haematuria in 20 (45%), mild proteinuria and
haematuria in 18 (40%) and heavy proteinuria in 7 (15%) patients. Renal biopsy was applied to 3 of the patients with nephrotic proteinuria
and revealed cresentic nephritis as the pathological diagnosis. In 2 (1.98%) patients acute renal failure occurred, One (0.99%) patient
required haemodialysis and the same patient died of acute pulmonary hemorrhage. Patients were followed up 7.28±4.83 months (2
months-2 years). 13 (12.9%) patients had recurrence of symptoms during the follow-up period.
Conclusion: Although HSP has a good prognosis, the course of the disease sometimes can be atypical with life threatening complications.
In acute phase, patients should be closely followed for complications whereas long term follow up is necessary for the evaluation of renal
involvement and recurrences.

Key words: Henoch Schönlein purpura, vasculitis, childhood

Article Language: Turkish English

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